Question

How do anti fungal drugs such as miconazole and amphotericin B function?

a.by disrupting the plasma membrane
b.by interfering with the processes of DNA replication and transcription
c.by inhibiting cell wall synthesis
d. by inhibiting protein synthesis

Answer 1

Antifungal drugs function by disrupting the plasma membrane of fungi.

Step-by-step explanation:

Antifungal drugs such as miconazole and amphotericin B function by disrupting the plasma membrane of fungi.

These drugs take advantage of the small biochemical differences between fungi and humans in the synthesis of sterols. Fungi use ergosterol, while human cells use cholesterol. Antifungal drugs target ergosterol synthesis, leading to membrane disruption and cell death.

Therefore, the correct answer is a. by disrupting the plasma membrane.