Final answer:
The correct administration of amiodarone in this scenario is to give a first dose of 300 mg via IV bolus followed by a second dose of 150 mg via IV bolus, as per ACLS guidelines.
Step-by-step explanation:
For an adult cardiac arrest patient in refractory ventricular fibrillation who has failed to respond to three defibrillation attempts and a single dose of epinephrine, the proper first and second dose of amiodarone would be:
- First dose: 300 mg via IV bolus.
- Second dose: 150 mg via IV bolus.
Therefore, the correct answer is A) Amiodarone 300 mg via IV bolus first dose and 150 mg the second IV dose. It is important to follow the Advanced Cardiac Life Support (ACLS) guidelines for medication administration during cardiac emergencies.