Final answer:
Emphysema is the medical condition that can cause problems in both internal and external processes of respiration.
Step-by-step explanation:
Emphysema is the medical condition most likely to cause problems with both the internal and external processes of normal respiration. Emphysema is a chronic lung disease characterized by the destruction of lung tissue, resulting in reduced surface area for gas exchange and increased air trapping in the lungs. This condition affects both the external process of ventilation, as the airways become obstructed and breathing becomes difficult, and the internal process of gas exchange, as the damaged alveoli impair the diffusion of oxygen and carbon dioxide.