Final answer:
The most appropriate class IIa intervention for a newborn requiring resuscitation with a low heart rate is 0.1 mg/mL of a 1:10,000 concentration of epinephrine delivered intravenously.
Step-by-step explanation:
The appropriate class IIa intervention for a newborn with a heart rate of 55 beats per minute that fails to respond after high-quality chest compressions and effective ventilations is 0.1 mg/mL of a 1:10,000 concentration of epinephrine delivered intravenously. When a brachial pulse is not palpable, and chest compressions are not effective in increasing the heart rate, intravenous (IV) or intraosseous (IO) access is critical for drug delivery. The recommended dose of epinephrine in neonatal resuscitation is 0.01-0.03 mg/kg of a 1:10,000 solution. The intramuscular route is not typically recommended for resuscitation in neonates.