Final answer:
The topical route of medication administration primarily provides local effect, but some medications can be absorbed into the bloodstream. Patients with skin abrasions are at risk of experiencing a systemic effect.
Step-by-step explanation:
The statement that are true regarding the topical route of medication administration are: 2) It primarily provides local effect, 4) Medications are absorbed through the skin rapidly, and 5) Patients with skin abrasions are at risk of systemic effect.The topical route of medication administration involves applying medications directly to the skin or mucous membranes. This allows the medications to have a local effect on the specific area of application. Examples of topical medications include creams, ointments, transdermal patches, and eye drops.Although the topical route is primarily used for local effect, some medications can be absorbed through the skin and enter the bloodstream, leading to a systemic effect. Patients with skin abrasions or other breaches in the skin barrier are at a greater risk of experiencing a systemic effect when using topical medications. It is important to consider these factors when using the topical route of medication administration.