Final answer:
Lipid solubility is a key factor that makes a medication more readily able to be absorbed and distributed. Nonpolar or lipid-soluble materials can easily pass through plasma membranes, allowing for faster diffusion. If a medication is lipid soluble, it can diffuse through the membrane and enter the cells more easily, increasing its ability to be absorbed and distributed.
Step-by-step explanation:
Lipid solubility is a key factor that makes a medication more readily able to be absorbed and distributed. Nonpolar or lipid-soluble materials can easily pass through plasma membranes, allowing for faster diffusion. If a medication is lipid soluble, it can diffuse through the membrane and enter the cells more easily, increasing its ability to be absorbed and distributed.
On the other hand, being in an ionic form or lipid insoluble can hinder the absorption and distribution of a medication. When a medication is ionic or lipid insoluble, it may not be able to cross the cell membrane efficiently and reach its intended target.
Furthermore, the state of being bound or unbound to plasma also affects the distribution of medication. Medication that is unbound to plasma is more readily available to cross membrane barriers, be distributed to tissues, and exert its pharmacological effects.