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When an active drug is metabolized into a second active metabolite, how is the action of that drug affected?

User Gnutt
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Final answer:

When an active drug is metabolized into a second active metabolite, the action of the drug can be affected in different ways. The second active metabolite can either have a similar pharmacological effect as the parent drug, leading to enhanced or prolonged drug action, or it can have a different pharmacological effect, leading to new therapeutic benefits or potential side effects.

Step-by-step explanation:

When an active drug is metabolized into a second active metabolite, the action of the drug can be affected in different ways. The second active metabolite can either have a similar pharmacological effect as the parent drug, leading to enhanced or prolonged drug action, or it can have a different pharmacological effect, leading to new therapeutic benefits or potential side effects.

For example, if the parent drug is metabolized into a more potent metabolite, the overall drug action may be increased. On the other hand, if the second active metabolite has different effects or is more toxic than the parent drug, it can lead to unexpected or undesired effects.

The action of the drug can also be influenced by factors such as the metabolism rate of the drug, the concentration of the metabolite in the body, and the binding affinity of the metabolite to its target receptors.

User Filipe Freire
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