Final answer:
The minor reactions to IV contrast can be localized such as hives and a flushed face, which are indicative of a mild Type I hypersensitivity reaction. The correct answer is D. 1 and 3 only, which includes a few hives and a flushed face as potential minor reactions.
Step-by-step explanation:
A minor reaction to the IV administration of a contrast agent can include a few hives, nausea, and a flushed face. Considering the nature of Type I hypersensitivity reactions, which can range from localized symptoms like hives and a flushed face to more severe systemic symptoms such as anaphylaxis, the correct answer to the question is D. 1 and 3 only. Minor reactions often include localized skin reactions, such as hives, and systemic symptoms might involve general flushing or a red face. These reactions are typically mild and manageably compared to severe reactions like anaphylaxis, which can present life-threatening symptoms such as swelling of the tongue and trachea, blockage of airways, and shock.