Question

A 29-year-old woman presents with lumps in the neck, fever, weight loss, night sweats, itching, and lethargy. She is ultimately diagnosed with stage IV Hodgkin's lymphoma and treated with chemotherapy followed by radiation. Four months later she develops shortness of breath, and chest CT scan reveals pulmonary fibrosis.

What chemotherapeutic agent is associated with this adverse reaction?

Answer 1

Bleomycin is the chemotherapeutic agent associated with pulmonary fibrosis as an adverse reaction, often used in treating Hodgkin's lymphoma.

Step-by-step explanation:

The chemotherapeutic agent commonly associated with the adverse reaction of pulmonary fibrosis is Bleomycin. Bleomycin is an antibiotic that also has antineoplastic properties, used to treat various types of cancer, including Hodgkin's lymphoma. One of its known side effects is its toxicity to the lungs, which can lead to pulmonary fibrosis. In the clinical scenario presented, the woman who developed shortness of breath after chemotherapy and was found to have pulmonary fibrosis on a CT scan likely experienced this as a side effect of her cancer treatment with Bleomycin.