Final answer:
The most appropriate medical therapy for the patient would be iron supplementation.
Step-by-step explanation:
The most appropriate medical therapy for the 45-year-old man with palpitations, easy fatigability, and chest pain on exertion would depend on the underlying cause of his symptoms and his lab results. Based on the provided information, the patient has a low hemoglobin level (Hb) of 8.8 g/dL, which indicates anemia. In addition, his ferritin level is low and his transferrin iron-binding capacity (TIBC) is elevated, suggesting iron deficiency anemia. Therefore, the most appropriate medical therapy for this patient would be iron supplementation.