Final answer:
Upon dilution of Roxanol, a Schedule II substance, with distilled water, the classification does not change. The resulting solution remains a Schedule II controlled substance, as only the concentration is altered, not the chemical nature.
Step-by-step explanation:
The question regarding the dilution of Roxanol (morphine sulfate) solution pertains to the classification of the resultant solution under the Controlled Substances Act (CSA). When 25cc of Roxanol (10mg/5cc) is removed from a 420cc bottle and diluted up to the 100cc mark with distilled water, the substance remains morphine sulfate, a Schedule II substance, as the dilution does not alter the chemical nature of the active pharmaceutical ingredient (morphine sulfate); it merely changes its concentration.
It's important to note that such manipulation of controlled substances must be performed by licensed professionals according to the regulations set forth by the Drug Enforcement Administration (DEA) and other relevant authorities.