Question

Which of the following statements is TRUE regarding antibiotic selection in this patient?

A. There may be chelation interactions between quinolones and multi-vitamins.
B. She cannot take cephalosporins because of penicillin allergy.
C. She cannot take macrolides because of allergy to erythromycin.
D. She cannot take macrolides because it cannot be given to patients taking aspirin.

Answer 1

The true statement is that there may be chelation interactions between quinolones and multi-vitamins. Patients with erythromycin allergy should avoid macrolides, while the claim about cephalosporins and aspirin with macrolides is not universally true.

Step-by-step explanation:

The correct statement regarding antibiotic selection for this patient is: There may be chelation interactions between quinolones and multi-vitamins. This is because quinolones can bind to the minerals contained in multi-vitamins, such as calcium or magnesium, and form chelates, which can inhibit the absorption of the antibiotic. Statement B is not necessarily always true, as not all patients with penicillin allergies are allergic to cephalosporins, and cross-reactivity is not universal. Statement C is true because if a patient is allergic to erythromycin, they are likely to be allergic to other macrolides due to the similar structure of these antibiotics. Lastly, statement D is incorrect because there is no contraindication for using macrolides in patients taking aspirin.

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