Final answer:
Methotrexate is contraindicated for a primgravida patient with rheumatoid arthritis due to its potential risk to the developing fetus. Other medications such as acetaminophen, cortisone injection, and simethicone may be considered safe and appropriate for the management of symptoms.
Step-by-step explanation:
Methotrexate is contraindicated for the patient with rheumatoid arthritis. Methotrexate is a commonly used disease-modifying anti-rheumatic drug (DMARD) for the treatment of rheumatoid arthritis. However, it is contraindicated in pregnant women or those who are planning to become pregnant due to its potential risk to the developing fetus. As the patient is a primgravida, meaning she is pregnant for the first time, methotrexate should not be used in her case. Other medications such as acetaminophen (a pain reliever), cortisone injection (to reduce inflammation), and simethicone (used for gas and bloating) may be considered safe and appropriate for the management of her symptoms.