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Which of the following medications are indicated for H. pylori-negative ulcers?

a. Nizatidine (Axid) and Clarithromycin (Biaxin)
b. Metronidazole (Flagyl) and Clarithromycin (Biaxin)
c. Omeprazole (Prilosec) and Nizatidine (Axid)
d. Omeprazole (Prilosec) and Tetracycline

1 Answer

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Final answer:

For H. pylori-negative ulcers, the appropriate medications are omeprazole (Prilosec), a proton pump inhibitor, and nizatidine (Axid), an H2-receptor antagonist. These drugs help to decrease stomach acid and promote healing of the ulcer without the use of antibiotics.

Step-by-step explanation:

The correct medications indicated for H. pylori-negative ulcers are omeprazole (Prilosec) and nizatidine (Axid). While antibiotics are used to treat H. pylori-positive ulcers, they are not recommended for H. pylori-negative ulcers. Medications that decrease stomach acid, such as H2-receptor antagonists like nizatidine and proton pump inhibitors (PPIs) like omeprazole, are the proper course of treatment in this case.

H2-receptor antagonists decrease the production of stomach acid, which helps ulcers heal, while PPIs suppress acid production even more effectively, aiding in the healing process as well. It's important to note that antacids may provide symptomatic relief but do not have the same healing effects as the aforementioned classes of drugs. Therefore, the direct answer to the student's question would be option c. Omeprazole (Prilosec) and Nizatidine (Axid).

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