Final answer:
Proton pump inhibitors like omeprazole are commonly used for the initial treatment of uncomplicated non-H. pylori peptic ulcer disease (PUD), and H2-receptor antagonists are another class of drugs for this purpose. Antibiotics are not indicated for non-H. pylori PUD initial treatment unless there is a specific indication.
Step-by-step explanation:
For the initial treatment of uncomplicated non-H. pylori peptic ulcer disease (PUD), medication to decrease stomach acid production is indicated. Proton pump inhibitors (PPIs) such as omeprazole (Prilosec) are commonly used. These medications work by reducing the amount of acid made in the stomach. H2-receptor antagonists, such as ranitidine (Zantac), famotidine (Pepcid AC), and cimetidine (Tagamet), are another class of drugs used to reduce gastric acid and treat ulcers. Unlike the treatment for H. pylori-related ulcers, antibiotics are not indicated in non-H. pylori PUD unless there is another specific indication for their use, such as a secondary bacterial infection.