Final answer:
SSRIs like Prozac, Zoloft, and Paxil are used to treat depression by increasing serotonin levels in the brain. SSRIs generally have fewer side effects than older classes of antidepressants, with escitalopram (Lexapro) often reported as having a favorable side effect profile.
Step-by-step explanation:
Selective serotonin reuptake inhibitors (SSRIs) are a class of drugs primarily used to treat depression by increasing serotonin levels in the central nervous system. SSRIs like fluoxetine (Prozac), sertraline (Zoloft), and paroxetine (Paxil) selectively block the reuptake of serotonin. It's important to note that SSRIs generally have fewer anticholinergic side effects compared to tricyclic antidepressants. When discussing the SSRIs with the least number of side effects (s/e), it appears that drugs such as escitalopram (Lexapro) are generally considered to have a favorable side effect profile among the newer SSRIs. However, patient response to SSRIs can vary, and it is crucial for treatment to be individualized under the guidance of a healthcare provider.
Reuptake inhibitors like SSRIs allow neurotransmitters such as serotonin to remain active in the synaptic cleft for an extended period, enhancing their effects. This mechanism is beneficial in the management of depressive disorders, which are often associated with reduced serotonin levels. Nevertheless, SSRIs are not instant solutions; patients typically need to take the medication for several weeks to notice an improvement.