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Fluoroquinolones should be avoided in patients that are/have all of the following except:

a. Pregnant
b. Younger than 18 years of age
c. Myasthenia gravis
d. Ulcerative colitis

User Sbleon
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1 Answer

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Final answer:

Fluoroquinolones should be avoided in specific patient groups due to certain risks. However, patients with ulcerative colitis are not explicitly contraindicated, unlike pregnant patients, individuals younger than 18, or those with myasthenia gravis.

Step-by-step explanation:

The question concerns the use of fluoroquinolones, a class of antibiotics, and in which patients they should be avoided. Fluoroquinolones should generally be avoided in patients who are pregnant, younger than 18, or have myasthenia gravis due to their associated risks. Patients with ulcerative colitis are not explicitly contraindicated for fluoroquinolone use according to the options provided. It's important to use these medications cautiously, as they have a unique site of action by inhibiting bacterial DNA gyrase and topoisomerase IV, which are essential for DNA replication and thus, bacterial growth. They are effective against a broad range of bacterial infections but are accompanied by potential side effects such as phototoxicity, neurotoxicity, cardiotoxicity, and an increased risk for tendon rupture.

User Farouk Osama
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