Final answer:
Concomitant nitrates should be used with caution in conditions such as recent MI, post-CVA, major surgery, or in any condition where exertion is contraindicated. Nitrates are medications used to treat cardiovascular conditions, but when combined with alpha blockers or in certain medical conditions, they can cause a dangerous drop in blood pressure. Therefore, individuals with cardiac disease and those taking alpha blockers should avoid using nitrates or consult their physician.
Step-by-step explanation:
Concomitant nitrates should be used with caution in conditions such as recent MI, post-CVA, major surgery, or in any condition where exertion is contraindicated.
Nitrates, such as those found in medications like nitroglycerin, are used to treat or improve symptoms of cardiovascular conditions including high blood pressure and heart failure. They work by relaxing and widening blood vessels, improving blood flow and reducing the workload on the heart.
However, when combined with alpha blockers (such as Flomax) or in certain medical conditions, nitrates can cause a dangerous drop in blood pressure. Therefore, it is important for individuals who are taking alpha blockers, have recently had a heart attack or stroke, undergone major surgery, or have any condition where exertion is contraindicated to exercise caution when using nitrates.