Final answer:
Among SSRIs, paroxetine (Paxil) is often reported to have higher rates of sexual side effects, including erectile dysfunction (ED), although this is a potential risk with all SSRIs. Bupropion (Wellbutrin) is noted to have fewer sexual side effects compared to other antidepressants.
Step-by-step explanation:
The SSRI associated with the common side effect of erectile dysfunction (ED) is not explicitly specified, as this side effect can potentially occur with various SSRIs. However, among selective serotonin reuptake inhibitors, paroxetine (known by the brand name Paxil) is often reported to have higher rates of sexual side effects, including ED.
SSRIs like fluoxetine (Prozac), sertraline (Zoloft), and paroxetine (Paxil) work by blocking the reuptake of serotonin into the presynaptic neuron, thus increasing serotonin levels in the synaptic cleft. This mechanism helps to alleviate depression, but it can also lead to various side effects, including sexual dysfunction. While sexual side effects are a potential risk with all SSRIs, bupropion (Wellbutrin) is distinctive in that it is one of the few antidepressants that is less likely to cause sexual side effects, since it variably inhibits serotonin and norepinephrine reuptake without affecting sexual function as much.
SSRIs are commonly prescribed for depression and are known to have a better side effect profile when compared to older classes of antidepressants, with generally fewer anticholinergic effects. Nevertheless, patients and healthcare providers should be mindful of potential side effects like sexual dysfunction when considering SSRI treatment options.