Final answer:
Individuals with sickle-cell anemia are at higher risk of death from a variety of complications associated with the disease, including acute chest syndrome, stroke, infections, and organ failure.
Step-by-step explanation:
Individuals with sickle-cell anemia are at higher risk of death from a variety of complications associated with the disease. The abnormal shape of the red blood cells in sickle-cell anemia can cause them to get stuck in narrow blood vessels, leading to blockages and reduced oxygen delivery to tissues. This can result in severe pain, organ damage, and even death. Common causes of death in individuals with sickle-cell anemia include acute chest syndrome, stroke, infections, and organ failure.