Final answer:
The most common site of spread for Non-Hodgkin lymphoma is the lymphatic system, and with progression, it can affect the liver, lungs, bones, and brain. Diffuse large B-cell lymphoma is a common subtype affecting B cells. Research and early treatment contribute to improved outcomes.
Step-by-step explanation:
The most common site of spread of Non-Hodgkin lymphoma (NHL) is typically the lymphatic system itself. However, as the disease progresses, it can metastasize to organs such as the liver, lungs, bones, and brain. Non-Hodgkin lymphoma includes various subtypes that may differ in their patterns of spread. One widespread subtype is diffuse large B-cell lymphoma (DLBCL), which is particularly known for affecting B cells. These lymphocytes can form tumors in lymph nodes and can spread through the lymphatic system to other nodes or through the blood to distant sites in a process known as metastasis. Though the lymphatic system is the primary network affected, organs frequently impacted by metastases from NHL include the liver, lungs, bones, and brain. Early detection and treatment are crucial for a better prognosis, and research efforts such as fundraising bike rides contribute to advancements in lymphoma treatment.