Final answer:
The anterior talofibular ligament is most commonly associated with lateral ankle sprains.
Step-by-step explanation:
The ligament that is most commonly associated with lateral ankle sprains is the anterior talofibular ligament. This ligament is located on the lateral side of the ankle and is responsible for stabilizing and supporting the joint. In an inversion ankle sprain, which is the most common type of ankle sprain, excessive inversion causes the talus bone to tilt laterally, resulting in damage to the anterior talofibular ligament.