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Can you list the contraindications to tPA therapy using the acronym "SAMPLE STaGES"?

User FuriousD
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Final answer:

The contraindications to tPA therapy can be remembered using the acronym "SAMPLE STaGES".

Step-by-step explanation:

The contraindications to tPA therapy can be remembered using the acronym "SAMPLE STaGES". Each letter represents a different contraindication:

  • Surgery or significant trauma within the past 2 weeks
  • Active bleeding or known bleeding diathesis
  • Malignant intracranial neoplasm (such as brain tumor)
  • Persistent high blood pressure (systolic >185 mm Hg or diastolic >110 mm Hg)
  • Large intracranial hemorrhage on head CT or MRI scan
  • Endocarditis or other evidence of infection in the blood
  • Severe liver disease
  • Traumatic or prolonged CPR (>10 minutes)
  • aNeurysm, arteriovenous malformation, or other intracranial structural abnormality
  • Gastrointestinal or genitourinary bleeding within the past 21 days
  • Evidence of recent active internal bleeding
  • Stroke or severe head trauma within the past 3 months
User GantengX
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