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Most common pathogen of endocarditis seen in history of colon CA or ulcerative colitis

User Zeyi Fan
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Final answer:

The most common pathogen associated with endocarditis in patients with a history of colon cancer or ulcerative colitis is Streptococcus gallolyticus, which can cause bacterial endocarditis.

Step-by-step explanation:

The most common pathogen associated with endocarditis in patients with a history of colon cancer or ulcerative colitis is Streptococcus gallolyticus (formerly known as Streptococcus bovis). S. gallolyticus is associated with gastrointestinal malignancies, including colon cancer, and it can cause bacterial endocarditis. This bacterium belongs to the group of non-enterococcal group D streptococci and can enter the bloodstream through lesions in the gastrointestinal tract, which may be more common in persons with ulcerative colitis or colon cancer. Treatment of endocarditis caused by S. gallolyticus involves a course of targeted antibiotics after appropriate blood culture and sensitivity testing, and in some cases, may necessitate surgical intervention, such as valve replacement.

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