Final answer:
Chronic kidney disease (CKD) can result in acid-base anomalies, electrolyte imbalances, and hematologic abnormalities. It can also disrupt the balance of calcium and phosphorus in the body. Symptoms can include metabolic acidosis, metabolic alkalosis, heart arrhythmias, and fatigue.
Step-by-step explanation:
Chronic kidney disease (CKD) can lead to various sequelae including acid-base anomalies, electrolyte imbalances, hematologic abnormalities, and disturbances in calcium and phosphate balance.
One of the consequences of CKD is metabolic acidosis, which occurs due to the accumulation of acidic substances in the body. This can lead to altered enzyme activity and increased excitability of cardiac and neuronal membranes.
Another important aspect of CKD is the imbalance of electrolytes such as increased serum phosphate and decreased urinary excretion of calcium and phosphorus. Patients may also experience metabolic alkalosis, heart arrhythmias, and other symptoms like excessive urination and fatigue.