Final answer:
The diagnosis suggested by the described symptoms, including 11;22 translocation and onion skin-like periosteal reaction, is Ewing Sarcoma. Treatment involves a multidisciplinary approach including chemotherapy, surgery, and potentially radiotherapy.
Step-by-step explanation:
The case described (11;22 translocation, X-ray imaging showing onion skin-like periosteal reaction, bone biopsy showing small, round, blue cells) is suggestive of a diagnosis of Ewing Sarcoma. This is a malignant small round blue cell tumor found predominantly in children and young adults. Treatment for Ewing Sarcoma typically includes a multidisciplinary approach, incorporating chemotherapy, surgery, and in some cases, radiotherapy. Depending on the stage and location of the tumor, various regimens can be considered. However, treatment strategies should be tailored to the individual by a team of oncologists and surgeons specialized in treating this type of cancer.