Question

"reduced EF in a pt with corse facial features and enlarged fingers. Dx? Acromegaly Diagnostic steps? check IGF-1 levels (high) glucose suppression test MRI Tx options? 1st line treatment is surgery prior to surgery you can give? octreotide, or bromocriptine (DA agonist), or pegvisomant (GH receptor blocker) most common cause of death? heart failure"

Answer 1

Reduced EF, coarse facial features, and enlarged fingers in a patient are suggestive of acromegaly, diagnosed by elevated IGF-1 levels, glucose suppression test, and MRI. Treatment options include surgery and medications like octreotide, bromocriptine, or pegvisomant, with heart failure being the most common cause of death.

Step-by-step explanation:

A patient presenting with reduced ejection fraction (EF), coarse facial features, and enlarged fingers may have a diagnosis of acromegaly. Acromegaly is a condition caused by the overproduction of Growth Hormone (GH) in adults. The diagnostic steps for acromegaly include checking IGF-1 levels, which are usually high, performing a glucose suppression test, and obtaining an MRI to look for a pituitary adenoma. Treatment options generally start with surgery to remove the adenoma if present. Prior to surgery, medications such as octreotide (somatostatin analog), bromocriptine (dopamine agonist), or pegvisomant (GH receptor blocker) can be used to control symptoms. The most common cause of death in untreated or uncontrolled acromegaly is heart failure.