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What are the three components of LPS of gram negative outer membrane?

User Jevon
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Final answer:

The three components of LPS of gram-negative outer membrane are Lipid A, Core Polysaccharide, and O side chain. Lipid A is toxic, the Core Polysaccharide serves as a link, and the O side chain is species-specific and can be used for identification.

Step-by-step explanation:

The Lipopolysaccharide (LPS) of the outer membrane of gram-negative bacteria consists of three main components:

  • Lipid A: Embedded in the outer membrane, Lipid A is the endotoxic component of LPS responsible for its toxic effects, such as fever and inflammation.
  • Core Polysaccharide: Links Lipid A to the O side chain and is a component of LPS that can vary in composition.
  • O side chain: Also known as O antigen, it is the outward-facing part of LPS and is composed of sugar-like molecules. The composition of the O side chain is species- and strain-specific, used for identifying pathogenic strains.

Together, these components make up the LPS, which helps in classifying bacteria and understanding the roles they play in triggering immune responses during infections.

User Mheinzerling
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