Final answer:
Facilitating the entry of antibiotics into the ear canal often involves the use of ear drops for topical treatment or systemic antibiotics in case of middle ear infections. Severe cases may require intravenous administration of antibiotics in a healthcare setting for better efficacy.
Step-by-step explanation:
The best way to facilitate the passage of an antibiotic into the ear canal for treating ear infections, such as otitis externa or otitis media with effusion, depends on the type of infection and the location within the ear. Antibiotics like polymyxin B, gentamicin, and some fluoroquinolones that are effective against Pseudomonas spp., might be applied as ear drops mixed with anti-inflammatory and antifungal agents. For infections like acute otitis media, systemic antibiotics such as amoxicillin or doxycycline might be necessary, particularly when ear drops can't reach the middle ear due to blockage of the eustachian tube. In more severe cases, such as when the infection is not responsive to oral antibiotics or when the patient cannot take oral medication, antibiotics may be administered intravenously in a healthcare setting to achieve higher plasma levels.