Final answer:
Angular cheilitis is frequently linked with iron deficiency anemia and vitamin-deficient anemias, especially those involving vitamin B12 and folate deficiencies.
Step-by-step explanation:
Angular cheilitis is commonly associated with iron deficiency anemia and vitamin-deficient anemias, particularly those involving insufficient vitamin B12 and folate. Iron deficiency anemia results from inadequate available iron to produce heme and can occur due to poor dietary intake, inability to absorb iron, or chronic bleeding. Vitamin-deficient anemias, such as pernicious anemia, arise from malabsorption of vitamin B12 and are frequently seen in conditions that affect the gastrointestinal tract, like Crohn's disease, as well as in those with dietary insufficiencies. Addressing the underlying cause is key to treating the anemia and associated symptoms like angular cheilitis.