Final answer:
The recommended first-line treatment for acute gout exacerbation is the use of nonsteroidal anti-inflammatory drugs (NSAIDs) such as ibuprofen or indomethacin.
Step-by-step explanation:
Recommended First-Line Treatment for Acute Gout Exacerbation:
The recommended first-line treatment for acute gout exacerbation is the use of nonsteroidal anti-inflammatory drugs (NSAIDs) such as ibuprofen or indomethacin. These medications help relieve pain, reduce inflammation, and lower uric acid levels in the body. NSAIDs are typically taken for a short duration until symptoms improve, and they are most effective when started within the first 24 hours of an acute gout attack.
Example:
For example, a commonly used NSAID for gout treatment is indomethacin. It works by inhibiting the enzyme cyclooxygenase (COX) and reducing the production of prostaglandins, which are responsible for inflammation and pain. By reducing inflammation, NSAIDs help alleviate symptoms and promote faster resolution of the gout attack.