Final answer:
The first-line drugs for JNC 8 include thiazide-diuretics, calcium channel blockers, ACE inhibitors, and ARBs.
Step-by-step explanation:
The first-line drugs for treating hypertension, according to the Eighth Joint National Committee on Prevention, Detection, Evaluation, and Treatment of High Blood Pressure (JNC 8), include:
- Thiazide-diuretics
- Calcium channel blockers
- Angiotensin converting enzyme inhibitors (ACE inhibitors)
- Angiotensin receptor blockers (ARBs)
These medications can be used alone or in combination to control blood pressure. However, ACE inhibitors and ARBs are not recommended to be used together. Most individuals with hypertension require more than one medication to effectively manage their blood pressure.