Final answer:
The first line therapy for ankylosing spondylitis involves NSAIDs to reduce inflammation and pain. Antibiotics like penicillin are not commonly used unless there is an infection. Other treatments may be considered if symptoms persist or are severe.
Step-by-step explanation:
The First Line Therapy for Ankylosing Spondylitis
The first line therapy for ankylosing spondylitis typically involves nonsteroidal anti-inflammatory drugs (NSAIDs), which are used to reduce inflammation and alleviate pain. These medications are deemed the initial treatment choice for managing the symptoms of this chronic inflammatory disease. In some severe cases, additional treatments, such as disease-modifying antirheumatic drugs (DMARDs) like sulfasalazine or methotrexate or biologic agents including TNF inhibitors, may be considered based on the patient's response to NSAIDs and the severity of their condition. It is not common practice to use oral or intravenous antibiotics such as penicillin for ankylosing spondylitis unless there is a coexisting infection that warrants such treatment.
Ankylosing spondylitis is a form of arthritis that primarily affects the spine, although other joints can also become involved. It causes inflammation of the spinal joints (vertebrae) that can lead to severe, chronic pain and discomfort. Early and appropriate treatment is crucial for managing symptoms and preventing the progression of the disease.