Final answer:
The first-line treatment for SLE dermatitis typically involves topical corticosteroids to reduce inflammation and alleviate skin symptoms; antimalarial medications like hydroxychloroquine are also frequently used.
Step-by-step explanation:
The first-line treatment for cutaneous manifestations of systemic lupus erythematosus (SLE), which may include itchy or sore patches of thick, red skin with silvery scales, commonly affects areas such as the elbows, knees, scalp, back, face, palms, and feet, involves the use of topical therapies. These typically include corticosteroid creams or gels, which help to reduce inflammation and alleviate symptoms. It is important to note that while autoantibodies in SLE can target various cells and lead to a wide range of symptoms, skin lesions and a characteristic sunlight-sensitive rash over the cheeks and bridge of the nose, known as the butterfly or lupus rash, are frequently observed. In some cases, antimalarial medications like hydroxychloroquine may also be prescribed due to their effectiveness in SLE skin disease. However, treatment must be carefully managed and tailored to each individual by their healthcare provider.