Final answer:
The CDC recommends a combination of ceftriaxone and azithromycin for the treatment of uncomplicated Gonorrhea to address both the infection and to prevent the spread of antibiotic resistance. Ceftriaxone is specifically chosen due to Neisseria gonorrhoeae resistance to various antibiotics, including some cephalosporins, penicillins, and tetracyclines.
Step-by-step explanation:
The preferred treatment for uncomplicated Gonorrhea infected patients is a combination regimen of ceftriaxone and azithromycin. According to the Centers for Disease Control and Prevention (CDC), this dual therapy is recommended to address both Neisseria gonorrhoeae and potential co-infection with Chlamydia trachomatis, which can often occur alongside gonorrhea. The combination of these two antibiotics also helps to slow the spread of antibiotic resistance, which is a significant concern with N. gonorrhoeae, and considered an urgent threat by the CDC. Treatments such as Keflex (Cephalexin), Penicillin, and Azithromycin alone are not the preferred first-line therapies for uncomplicated Gonorrhea. Given the increasing antibiotic resistance observed in N. gonorrhoeae, including resistance to some cephalosporins, penicillins, and tetracyclines, it is crucial to follow the CDC's recommendations for effective treatment. The use of Ceftriaxone, a cephalosporin, is particularly important since N. gonorrhoeae has shown some resistance to other antibiotics within this class. In cases where gonorrhea is confirmed to be present without chlamydia, the CDC currently recommends a single dose of Ceftriaxone for treatment.