Final answer:
Strabismus is the disorder where misaligned or unbalanced eye muscles cause the eyes to look in different directions. Options like Amblyopia, Presbyopia, Iritis, and Astigmatism refer to other issues related to vision.
Step-by-step explanation:
The disorder in which misaligned or unbalanced eye muscles cause the eyes to appear to be looking in two different directions is Strabismus (E). This condition can lead to the eyes not working together properly, and it can affect depth perception and cause double vision.
It is important to note that the other options listed pertain to different vision issues:
Amblyopia is often a result of strabismus where one eye is weaker than the other and the brain favors the stronger eye. Presbyopia involves the loss of the eye's ability to focus on close objects and is associated with aging. Iritis is inflammation of the iris and not related to muscle alignment. Finally, Astigmatism is related to an irregular curvature of the cornea or lens causing blurred vision.