Final answer:
The direct answer to the exception regarding Japan's 'closing' to the West is the option stating a 'culturally affirming Dutch Studies program for the naturalized Dutch and for Dutch-Japanese in Japan'. This is incorrect, as the Dutch were restricted to Dejima Island, but their limited interaction led to 'Dutch Learning', which allowed for some Western knowledge to reach Japan.
Step-by-step explanation:
The "closing" of Japan to the Western world, known as sakoku, was a significant period in Japanese history occurring during the Edo period. An exception to the isolated stance was the Dutch Learning, or Rangaku, which allowed limited Western knowledge and goods into Japan. Three main points characterized the isolation policy: strong efforts to eradicate Christianity with the Edo Shogunate's anti-Christian campaign, a strict control over foreign trade by confining it to Nagasaki with primarily Chinese and Dutch merchants, and the prohibition of Japanese from traveling abroad to maintain neo-Confucian societal order.
However, the statement that a 'culturally affirming "Dutch Studies" program for the naturalized Dutch and for Dutch-Japanese in Japan' characterized the period is incorrect. Instead, the Dutch were confined to Dejima Island in Nagasaki harbor, but they inadvertently contributed to Rangaku, which became a channel through which Japan received Western knowledge. Thus, the Dutch presence led to a selective permeation of Western science and medicine, which laid the groundwork for Japan's later modernization, particularly during the Meiji Restoration when Japan sought to learn from the West.