Final answer:
The statement is true; DNA unwinds at multiple origins of replication. Helicases open up the DNA creating replication forks, while topoisomerases and single-strand binding proteins aid in the process.
Step-by-step explanation:
The statement that DNA unwinds at several points is true. During DNA replication, the molecule unwinds at the origin of replication. Enzymes called helicases work to open up the DNA, forming replication forks which are extended in both directions. Proteins such as single-strand binding proteins stabilize the unwound DNA and prevent it from rewinding. Moreover, enzymes known as topoisomerases relieve the strain caused by unwinding at the region ahead of the replication forks. This coordinated action ensures that the DNA is properly unwound and ready for the replication process.