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A child weighs 85lbs and is 50 inches tall. the recommended dose of vincristine is 1.5-2mg/m² once a week. the concentration available is 1mg/ml. what is the recommended dosage range for this child?

User Tully
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1 Answer

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Final answer:

The recommended dosage range for the child is 1.746 mg to 2.328 mg.

Step-by-step explanation:

The recommended dosage range for this child can be calculated using the formula:

Dosage = (weight in lbs / 2.2) × (dose in mg/m²)

First, we convert the weight from lbs to kg by dividing the weight by 2.2: 85 lbs / 2.2 = 38.64 kg

Second, we calculate the body surface area (BSA) using the formula:

BSA = √(height in cm × weight in kg / 3600)

Converting the height from inches to cm: 50 inches × 2.54 cm/inch = 127 cm.

Substituting the values into the formula:

BSA = √(127 cm × 38.64 kg / 3600)

= √(1.3569)

= 1.164 m²

Finally, we calculate the recommended dosage range:

Recommended dosage range = BSA × (dose in mg/m²)

For a dose of 1.5-2mg/m², the recommended dosage range would be: 1.164 m² × 1.5 mg/m²

= 1.746 mg - 1.164 m² × 2 mg/m²

= 2.328 mg

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