Question

Leukocyte adhesion deficiency (LAD) is a rare autosomal recessive disorder characterized by the inability of neutrophils to recognize C3b-bound pathogens. What is the most likely symptom of this disease?

A) Decrease in white cell count
B) Increase in pus production
C) Bacterial infections difficult to control
D) Autoimmunity

Answer 1

The most likely symptom of Leukocyte adhesion deficiency (LAD) is bacterial infections that are difficult to control, as the disorder impairs neutrophils' ability to respond properly to infections.

Step-by-step explanation:

Leukocyte adhesion deficiency (LAD) is a disorder that affects the immune system's ability to function correctly. Neutrophils, a type of leukocyte, are unable to recognize C3b-bound pathogens due to this deficiency. The most likely symptom of LAD is C) Bacterial infections difficult to control.

This occurs because neutrophils are essential for the body's first line of defense against bacterial infections. When neutrophils cannot adhere to blood vessel walls and migrate to sites of infection, bacterial infections can proliferate without being adequately controlled.