Final answer:
The Institutional Biosafety Committee must have at least five members to meet NIH guidelines, incorporating diverse representatives to oversee biological research safety. The correct answer is option 3.
Step-by-step explanation:
The minimum number of members an Institutional Biosafety Committee (IBC) must have to comply with the NIH guidelines is 5.
The IBC is responsible for reviewing and approving research protocols involving biological materials to ensure compliance with biosafety guidelines. The committee typically consists of scientists, biosafety officers, and other relevant personnel.
Having a diverse group of members with different areas of expertise helps ensure that the research is conducted safely and effectively.