Question

The project that you are working on was initiated in response to the growing threat of antibiotic resistance in both hospital and community settings. even in the early discovery and development phase, it is important to think ahead to try to minimize the likelihood that bacteria will be able to evolve resistance to your new drug. understanding how resistance emerges is an essential part of this process. which of the following statements is not true regarding the evolution of antibiotic resistance in bacteria?

A. Antibiotic resistance is a growing threat in hospital and community settings.
B. Minimizing the likelihood of bacterial resistance is crucial in the early stages of drug development.
C. Understanding the emergence of resistance is not essential in the drug development process.
D. The project aims to address the threat of antibiotic resistance.

Answer 1

Understanding how antibiotic resistance emerges in bacteria is crucial in the drug development process. Misstating the importance of this understanding is the false statement among those mentioned regarding antibiotic resistance. Therefore, the correct option is C.

Step-by-step explanation:

The question pertains to the evolution of antibiotic resistance in bacteria and identifies a false statement among several about resistance. The false statement in question is: 'Understanding the emergence of resistance is not essential in the drug development process.'

Antibiotic resistance is indeed an increasing concern; the project's goal mentioned in the question aims to address this issue. The development of resistance can occur due to overuse or misuse of antimicrobial drugs, inappropriate use, subtherapeutic dosing, and patient noncompliance. The emergence of resistance is a key consideration in drug development because the new drugs must be effective against these resistant strains. Thus, it is false to suggest that understanding resistance is not essential during drug development.

Since antibiotic-resistant bacteria are an evolving environmental issue, learning about bioinformatics, site-directed mutagenesis, nucleic acid manipulation techniques, and fluorescence binding assays can be crucial for early development stages of new drugs to minimize future resistance.