Question

Cancer-associated fibroblasts induce antigen-specific deletion of cdt cells to protect tumour cells

a) true
b) false

Answer 1

The claim that cancer-associated fibroblasts induce antigen-specific deletion of cytotoxic T cells is false. Instead, cytotoxic T cells are essential for targeting and destroying cancer cells by recognizing tumor antigens on their surfaces. The statement is false.

Step-by-step explanation:

• The statement that cancer-associated fibroblasts induce antigen-specific deletion of cytotoxic T (CD8+) cells to protect tumor cells is false. Cytotoxic T cells are a critical component of the adaptive immune response against cancer.
• These cells recognize and destroy cancer cells by identifying tumor antigens presented on the surface of these cells.
• The immune system's response to tumors involves cell-mediated responses, where cytotoxic T cells and NK (natural killer) cells can induce apoptosis in the abnormal cells that express these antigens.
• Cancer-associated fibroblasts can modulate the tumor environment, but they do not specifically induce antigen-specific deletion of cytotoxic T cells to protect tumor cells.