Question

Based on the research into the role of glutamate circuits in the brain, you might predict that a reduction in this neurotransmitter would

a.hinder memory formation.
b.lead to facial tics or muscle tremors.
c.result in a decreased ability to modulate pain.
d.produce sleep disorders.

Answer 1

A reduction in glutamate, a critical neurotransmitter for learning and memory, would likely hinder memory formation due to its role in synaptic plasticity and cognitive function.

Step-by-step explanation:

Based on research into the role of glutamate circuits in the brain, a reduction in this neurotransmitter would most likely hinder memory formation. Glutamate is the main excitatory neurotransmitter in the CNS and is involved in crucial physiological mechanisms such as synaptic plasticity, long-term potentiation (LTP), and long-term depression (LTD), which underlie processes of learning and memory.

Glutamatergic neurons are vital for cognitive functions and any disruptions in glutamatergic signaling have been associated with neurological and neurodegenerative disorders. A decrease in glutamate would disrupt the normal synaptic activity and could impair the facilitation of learning and memory consolidation, as glutamate is critical in the enhancement of synaptic connections that occurs in memory formation.