Final answer:
True: studying atoms is challenging due to their tiny size, requiring sophisticated tools like electron microscopes and mass spectrometers to observe indirectly and understand their properties.
Step-by-step explanation:
True. One difficulty in studying atoms is that our current tools do not allow us to easily study such small objects directly. The unprecedented smallness of atoms presents unique challenges when trying to observe them or measure their properties.
To understand the properties and behavior of atoms, scientists use a range of highly sophisticated equipment, such as electron microscopes and mass spectrometers. Tools such as the scanning tunneling electron microscope have granted us the ability to not only detect individual atoms but also to observe their substructures, like electron shells and nuclei. Nevertheless, imagery at this scale still involves indirect methods, and the direct visualization of atoms remains a complex task.
Despite these challenges, our understanding of the atom has significantly evolved. Experimental confirmation of theoretical models of the atom has come from a variety of experiments and findings in physics. This broad array of evidence and advanced technology allows us to gain insights into the miniscule world of atoms, albeit not without the aid of instruments that enhance our capability to probe the tiny scale where atoms exist.