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Why does ACOG only recomment short-term use of *HRT (hormone replacement therapy)*? What are the risks?

User Shader
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Final answer:

ACOG recommends short-term use of HRT due to risks such as breast cancer, cardiovascular problems, and blood clots. Studies, including a notable one from 2002, have shown higher incidences of such conditions with long-term use. Guidelines suggest minimal effective dosage and duration, with regular health screenings.

Step-by-step explanation:

The American College of Obstetricians and Gynecologists (ACOG) recommends short-term use of Hormone Replacement Therapy (HRT) mainly due to the increased health risks associated with its long-term use. While HRT can alleviate menopausal symptoms such as hot flashes, night sweats, and vaginal dryness, as well as prevent bone loss that can lead to osteoporosis, studies have implicated HRT in increasing the risk of several serious health conditions. The most notable increased risks include breast cancer, stroke, heart attack, blood clots, ovarian cancer, endometrial cancer, gall bladder disease, and possibly dementia.

These concerns originally arose following a significant study by the Women's Health Initiative in 2002 that had to be prematurely terminated due to a higher-than-expected incidence of breast cancer and lack of cardiovascular benefits in estrogen-only HRT patients. To minimize the risks while still providing symptom relief, current guidelines suggest using the lowest effective dose of HRT for the shortest duration needed, typically less than five years, and include regular health screenings like pelvic and breast exams for those undergoing treatment.

User Pete Morris
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