Question

You have a patient that present with a *fundal height > GA* and an *elevated mAFP* - what is the most likely cause of this?

Answer 1

The most likely cause is relapse with endodermal sinus tumor in a child previously treated for teratoma.

Step-by-step explanation:

The most likely cause of a patient presenting with a fundal height greater than gestational age (GA) and an elevated mAFP is relapse with endodermal sinus tumor in a child previously treated for teratoma. This can be monitored in cancer survivors after treatment, and an elevated mAFP suggests the possibility of relapse.

Some other possible causes of a fundal height greater than GA include an abnormally enlarged anterior pituitary or hypertrophy of the thyroid's follicle cells. However, in the context of a patient with an elevated mAFP, relapse with endodermal sinus tumor is the most likely cause.