Final answer:
The nurse should ask the patient if they are aware of the side effects of chemotherapy to ensure they are well-informed about their treatment.
Step-by-step explanation:
The most appropriate question that the nurse should ask the patient is: Are you aware of the side effects of chemotherapy? This question is important because it ensures that the patient is well-informed about what to expect during their treatment. Knowing the side effects of chemotherapy allows the patient to make informed decisions about their health and well-being.