Final answer:
Barbara's infection did not respond to oxacillin therapy because the isolate of Staphylococcus aureus causing the infection was methicillin-resistant (MRSA), a type of bacteria that is resistant to many common antibiotics. Alternative antibiotics, such as vancomycin, are needed to effectively treat MRSA infections.
Step-by-step explanation:
Barbara's infection did not respond to oxacillin therapy because the isolate of Staphylococcus aureus causing the infection was methicillin-resistant (MRSA). MRSA is a type of bacteria that is resistant to many common antibiotics, including oxacillin. Therefore, alternative antibiotics, such as vancomycin, are needed to effectively treat the infection.
MRSA is a major problem in healthcare settings, as it can cause serious and potentially life-threatening infections that are difficult to treat. It is important for healthcare providers to be aware of the presence of MRSA and to use appropriate antibiotics when treating infections caused by this type of bacteria.
In Barbara's case, her doctor changed her antibiotic therapy to vancomycin, which is an effective treatment for MRSA infections. Removal of the port and venous catheter may also have been necessary to fully resolve the infection.