Final answer:
Fluoroquinolone antibiotics and high-dose or prolonged corticosteroid use have been associated with tendonitis, tendon rupture, and cartilage damage. Tendon injuries can result from microtrauma due to repetitive use, and proper preventive measures and adequate rest are key to recovery and reducing injury risk.
Step-by-step explanation:
The drugs that have been linked to the development of tendonitis, tendon rupture, and cartilage damage are a class of antibiotics known as fluoroquinolones. This class includes drugs such as ciprofloxacin and levofloxacin. These drugs can contribute to these adverse effects by disrupting the normal function of connective tissue cells and collagen synthesis, which are vital for tendon and cartilage health. Additionally, corticosteroids, which are often used to treat inflammation, can also weaken tendons and lead to tendon rupture when used in high doses or for prolonged periods.
In the context of musculoskeletal disorders, repetitive movements and overuse can lead to microtrauma, initiating an inflammatory response that can result in tendonitis. Over time, especially in the case of inadequate rest and recovery for the tendon, these stresses can lead to severe injury, including tendon rupture. Preventive measures such as proper stretching, cross training, and technique improvement are essential to decrease the risk of developing tendinitis and facilitate the recovery process.